why does it make sense that metabolism of pyruvate to acetyl-coa would be inhibited by fatty acids? speculate why the production of metabolic acids

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24-11-2022
Biology

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why does it make sense that metabolism of pyruvate to acetyl-coa would be inhibited by fatty acids? speculate why the production of metabolic acids

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NomulaHarsh NomulaHarsh · Answer 1 · 2022-11-30T13:11:56+01:00

Because the inhibitory products of the pyruvate dehydrogenase reaction , that is NADH and acetyl -coA are also produces during beta-oxidation of fatty acids .

which resulted in conversion of active pyruvate dehydrogenase into it's inactive form .

The metabolism of pyruvate is affected by ATP/ADP , NADH/NAD+ and acetyl-CoA/CoA ratios .

Hence , that is the reason for inhibition of pyruvate to acetyl-coa .

To learn more about pyruvate from the given link https://brainly.com/question/16346028

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